The association between dengue immunoglobulin G titres with previous clinical dengue infection and white cell counts in Cuban children: A population-based study.

ABSTRACT:

Background

The prevalence of dengue infection is increasing globally. There are few prospective population-based surveillance studies of the immunological and inflammatory consequences of exposure to dengue virus in young children.

Objective

To study the association between serologically confirmed prior medical diagnosis of dengue infection and blood measures of systemic inflammation with dengue virus immunoglobulin G levels.

Methods

A population-based study of healthy three-year old children living in Havana, Cuba.

Results

865 individuals provided a blood sample. Fourteen (1.6%) had a prior medical diagnosis of dengue infection, and 851 individuals had no prior medical diagnosis. There was no difference in the serum immunoglobulin G titres between these groups

SUBMITTER: Suarez-Medina R 

PROVIDER: S-EPMC6261577 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature