Evaluation of flicker induced hyperemia in the retina and optic nerve head measured by Laser Speckle Flowgraphy.

ABSTRACT:

Purpose

The coupling between neural activity and blood flow is a physiological key principle of ocular blood flow regulation. The current study was performed to investigate whether Laser speckle flowgraphy (LSFG), a commercially available technique for measuring blood flow, is capable to assess flicker-induced haemodynamic changes in the retinal and optic nerve head (ONH) circulation.

Methods

Twenty healthy subjects were included in this cross sectional study. A commercial LSFG instrument was used to measure blood flow at the ONH as well as in retinal vessels before and during stimulation with flickering light. Mean blur rate (MBR), a measure of relative blood flow velocity, was obtained for the ONH and relative flow volume (RFV) a measure of relative blood flow of the respe

SUBMITTER: Fondi K 

PROVIDER: S-EPMC6261588 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature