Bariatric surgery and birth defects: A systematic literature review.

ABSTRACT:

Background

Bariatric procedures are on the rise. The risk of birth defects in pregnancies following such procedures may be increased (eg, due to nutrient deficiencies) or decreased (eg, due to decreased maternal body mass index, BMI).

Methods

We conducted a systematic literature review of the association between bariatric surgery and birth defects using Ovid MEDLINE and PubMed (1946-2017). Information was abstracted on study design, exposures, outcomes, covariates and estimates of association.

Results

Fifteen studies met our inclusion criteria: 14 evaluated the outcome of any birth defect, and one evaluated neural tube defects. Estimates of association between bariatric surgery and birth defects were available for nine studies and ranged from 0.6 to 1.9 (all 95% confi

SUBMITTER: Benjamin RH 

PROVIDER: S-EPMC6261675 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature