Trauma exposure acutely alters neural function during Pavlovian fear conditioning.

ABSTRACT: Posttraumatic stress disorder (PTSD) is associated with dysfunction of the neural circuitry that supports fear learning and memory processes. However, much of what is known about neural dysfunction in PTSD is based on research in chronic PTSD populations. Less is known about neural function that supports fear learning acutely following trauma exposure. Determining the acute effects of trauma exposure on brain function would provide new insight into the neural processes that mediate the cognitive-affective dysfunction associated with PTSD. Therefore, the present study investigated neural activity that supports fear learning and memory processes in recently Trauma-Exposed (TE) and Non-Trauma-Exposed (NTE) participants. Participants completed a Pavlovian fear conditioning procedure during fun

SUBMITTER: Harnett NG 

PROVIDER: S-EPMC6261786 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature