Radiomics improves efficiency for differentiating subclinical pheochromocytoma from lipid-poor adenoma: a predictive, preventive and personalized medical approach in adrenal incidentalomas.

ABSTRACT:

Objectives

This study aims to define a radiomic signature for pre-operative differentiation between subclinical pheochromocytoma (sPHEO) and lipid-poor adrenal adenoma (LPA) in adrenal incidentaloma. The goal was to apply a predictive, preventive, and personalized medical approach to the management of adrenal tumors.

Patients and methods

This retrospective study consisted of 265 consecutive patients (training cohort, 212 (LPA, 145; sPHEO, 67); validation cohort, 53 (LPA, 36; sPHEO, 17)). Computed tomography (CT) imaging features were evaluated, including long diameter (LD), short diameter (SD), pre-enhanced CT value (CT_pre), enhanced CT value (CT_post), shape, homogeneity, necrosis or cystic degeneration (N/C). Radiomic features were extracted and then w

SUBMITTER: Yi X 

PROVIDER: S-EPMC6261906 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature