Clinical Utility of Definitive Drug⁻Drug Interaction Testing in Primary Care.

ABSTRACT: Drug⁻drug interactions (DDIs) are a leading cause of morbidity and mortality. New tools are needed to improve identification and treatment of DDIs. We conducted a randomized controlled trial to assess the clinical utility of a new test to identify DDIs and improve their management. Primary care physicians (PCPs) cared for simulated patients presenting with DDI symptoms from commonly prescribed medications and other ingestants. All physicians, in either control or one of two intervention groups, cared for six patients over two rounds of assessment. Intervention physicians were educated on the DDI test and given access to these test reports when caring for their patients in the second round. At baseline, we saw no significant differences in making the DDI diagnosis (p = 0.071) or DDI-

SUBMITTER: Peabody J 

PROVIDER: S-EPMC6262337 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature