Performance comparison of ventricular and arterial dP/dt_max for assessing left ventricular systolic function during different experimental loading and contractile conditions.

ABSTRACT:

Background

Maximal left ventricular (LV) pressure rise (LV dP/dt_max), a classical marker of LV systolic function, requires LV catheterization, thus surrogate arterial pressure waveform measures have been proposed. We compared LV and arterial (femoral and radial) dP/dt_max to the slope of the LV end-systolic pressure-volume relationship (Ees), a load-independent measure of LV contractility, to determine the interactions between dP/dt_max and Ees as loading and LV contractility varied.

Methods

We measured LV pressure-volume data using a conductance catheter and femoral and radial arterial pressures using a fluid-filled catheter in 10 anesthetized pigs. Ees was calculated as the slope of the end-systolic pressure-volume relationship during a trans

SUBMITTER: Monge Garcia MI 

PROVIDER: S-EPMC6262953 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature