Maternal periconceptional consumption of sprouted potato and risks of neural tube defects and orofacial clefts.

ABSTRACT:

Background

The association between maternal consumption of sprouted potato during periconceptional period on the development of neural tube defects (NTDs) or orofacial clefts (OFCs) remains unclear. We aimed to examine the association between maternal consumption of sprouted potatoes during periconceptional period and risks of NTDs or OFCs.

Methods

Subjects included 622 NTD cases, 135 OFC cases and 858 nonmalformed controls, were recruited from a case-control study in Shanxi Province of northern China between 2002 and 2007. Information on demographics, maternal sprouted potato consumption, lifestyle behaviors and folic acid supplementation was collected.

Results

Consumption of sprouted potatoes was associated with elevated odds of total NTDs (OR = 2.20; 95% CI, 1.12-4

SUBMITTER: Ni W 

PROVIDER: S-EPMC6262956 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature