A mathematical model of biomedical interventions for HIV prevention among men who have sex with men in China.

ABSTRACT:

Background

The new HIV treatment guidelines in China recommend antiretroviral therapy (ART) for all people living with HIV, but significant gaps in implementation still exist. Pre-exposure prophylaxis (PrEP) can effectively reduce the risk of HIV transmission among men who have sex with men (MSM). This study assessed the epidemiological impact and cost effectiveness of PrEP, enhanced biomedical interventions and their combination among MSM in China.

Methods

A deterministic mathematical model was developed and projected over 20 years to assess the impact of the PrEP, biomedical interventions and their combinations. Incidence and prevalence of HIV were measured, and cost-effectiveness was assessed using incremental cost (international dollars, Int.$) per quality-adjusted life

SUBMITTER: Li J 

PROVIDER: S-EPMC6263536 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature