Development of a micro-tissue-mediated injectable bone tissue engineering strategy for large segmental bone defect treatment.

ABSTRACT:

Background

Bone tissue engineering is not widely used in clinical treatment. Two main reasons hide behind this: (1) the seed cells are difficult to obtain and (2) the process of tissue engineering bone construction is too complex and its efficiency is still relatively low. It is foreseeable that in the near future, the problem of seed cell sources could be solved completely in tissue engineering bone repair. As for the complex process and low efficiency of tissue engineering bone construction, usually two strategies would be considered: (1) the construction strategy based on injectable bone tissue and (2) the construction strategy based on osteogenic cell sheets. However, the application of injectable bone tissue engineering (iBTE) strategy and osteogenic cell sheet strategy is lim

SUBMITTER: Wu D 

PROVIDER: S-EPMC6263540 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature