Preservation of Bone Tissue Integrity with Temperature Control for In Situ SR-MicroCT Experiments.

ABSTRACT: Digital volume correlation (DVC), combined with in situ synchrotron microcomputed tomography (SR-microCT) mechanics, allows for 3D full-field strain measurement in bone at the tissue level. However, long exposures to SR radiation are known to induce bone damage, and reliable experimental protocols able to preserve tissue properties are still lacking. This study aims to propose a proof-of-concept methodology to retain bone tissue integrity, based on residual strain determination using DVC, by decreasing the environmental temperature during in situ SR-microCT testing. Compact and trabecular bone specimens underwent five consecutive full tomographic data collections either at room temperature or 0 °C. Lowering the temperature seemed to reduce microdamage in trabecular bone but had minimal eff

SUBMITTER: Pena Fernandez M 

PROVIDER: S-EPMC6266162 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature