Mean platelet component and mean platelet volume as useful screening markers for myelodysplastic syndrome.

ABSTRACT:

Background

Hematologic disorders, including myelodysplastic syndrome (MDS), are difficult to identify in routine hematologic examinations using automated hematology analyzers. However, the practical uses of mean platelet component and mean platelet volume (MPV) measured by these analyzers as screening markers for MDS, remain unclear.

Methods

Mean platelet component and MPV values were measured in the peripheral blood of patients with MDS, aplastic anemia, idiopathic thrombocytopenic purpura, myeloproliferative neoplasms, and in healthy controls using an automated hematologic analyzer. Cutoff values for discriminating between the MDS group and healthy controls were determined by recursive partitioning analysis.

Results

Mean platelet component was significantly lower in

SUBMITTER: Masutani R 

PROVIDER: S-EPMC6266360 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature