The Effect of Alginate in Gastroesophageal Reflux in Infants.

ABSTRACT:

Background

Guidelines are contradictory regarding the use of alginate in infants with persisting gastroesophageal reflux (GER). While The British National Institute for Health and Care (NICE) guidelines consider alginate as a treatment option, the guidelines of the European and North-American Societies for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN, NASPGHAN) do not recommend alginates.

Aims

We assessed the efficacy of alginate to reduce GER episodes in infants.

Methods

In a prospective, observational study, we consecutively enrolled all infants referred for pH-multiple intraluminal impedance (pH-MII) recording because of persisting GER symptoms not responsive to behavior and dietetic modifications. A 48-h pH-MII was performed in all infants; a base

SUBMITTER: Salvatore S 

PROVIDER: S-EPMC6267531 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature