Predictive value of interim positron emission tomography in diffuse large B-cell lymphoma: a systematic review and meta-analysis.

ABSTRACT:

Purpose

Diffuse large B-cell lymphoma (DLBCL) represents the most common subtype of non-Hodgkin lymphoma. Most relapses occur in the first 2 years after diagnosis. Early response assessment with ¹⁸F-fluoro-2-deoxy-D-glucose (¹⁸F-FDG) positron emission tomography (PET) may facilitate early change of treatment, thereby preventing ineffective treatment and unnecessary side effects. We aimed to assess the predictive value of visually-assessed interim ¹⁸F-FDG PET on progression-free survival (PFS) or event-free survival (EFS) in DLBCL patients treated with first-line immuno-chemotherapy regimens.

Methods

For this systematic review and meta-analysis Pubmed, Embase, and the Cochrane Library were searched until July 11, 2017. Prospective and retrospe

SUBMITTER: Burggraaff CN 

PROVIDER: S-EPMC6267696 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature