CDCA5 overexpression is an Indicator of poor prognosis in patients with hepatocellular carcinoma (HCC).

ABSTRACT:

Background

Accurate and early prognosis of disease is essential to clinical decision making, particularly in diseases, such as HCC, that are typically diagnosed at a late stage in the course of disease and therefore carry a poor prognosis. CDCA5 is a cell cycle regulatory protein that has shown prognostic value in several cancers.

Methods

We retrospectively evaluated 178 patients with HCC treated with curative liver resection between September 2009 and September 2012 at Nanchong Central Hospital in Nanchong, Sichuan Province, China. Patients were screened for their CDCA5 expression levels and assigned to either the high or low expression group. Patient demographics, comorbidities, clinicopathologic data, such as tumor microvascular invasion status and size, and long-term out

SUBMITTER: Tian Y 

PROVIDER: S-EPMC6267780 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature