Glycated hemoglobin A1c level on the day of emergency surgery is a marker of premorbid glycemic control: a retrospective observational study.

ABSTRACT:

Background

Current international guideline recommends to maintain blood glucose level ≤ 180 mg/dL in acute ill patients, irrespective of presence of premorbid diabetes. However, there are studies suggested that optimal acute glycemic control should be adjusted according to premorbid glycemic control in patients with chronic hyperglycemia. Accordingly, to obtain the information of premorbid glycemic control would be relevant. However, the HbA1c level on the day of the emergency operation (HbA1c-ope) might not be useful as a surrogate of premorbid chronic glycemic control, since glucose metabolism can be affected by inflammation, severity of illness and surgical invasion.

Methods

We hypothesized that HbA1c-ope reflects pre-morbid glycemic control. To assess this hypothesis, we

SUBMITTER: Hokka M 

PROVIDER: S-EPMC6267889 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature