Side-chain modifications of highly functionalized 3(2H)-furanones.

ABSTRACT: A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives. The isoxazole was prepared by a [3+2] 1,3-dipolar cycloaddition reaction between 3-butyn-2-ol and nitrile oxide.

SUBMITTER: Nardini V 

PROVIDER: S-EPMC6268025 | biostudies-literature | 2012 Oct

REPOSITORIES: biostudies-literature