Allylation of functionalized aldehydes by potassium allyltrifluoroborate catalyzed by 18-crown-6 in aqueous media.

ABSTRACT: An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described. The reaction utilizes a catalytic amount of 18-C-6 in biphasic media under open atmosphere and room temperature to provide the corresponding homoallylic alcohols in high yields and without the necessity of any subsequent purification.

SUBMITTER: Barbosa FC 

PROVIDER: S-EPMC6268519 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature