Canonical Causal Diagrams to Guide the Treatment of Missing Data in Epidemiologic Studies.

ABSTRACT: With incomplete data, the "missing at random" (MAR) assumption is widely understood to enable unbiased estimation with appropriate methods. While the need to assess the plausibility of MAR and to perform sensitivity analyses considering "missing not at random" (MNAR) scenarios has been emphasized, the practical difficulty of these tasks is rarely acknowledged. With multivariable missingness, what MAR means is difficult to grasp, and in many MNAR scenarios unbiased estimation is possible using methods commonly associated with MAR. Directed acyclic graphs (DAGs) have been proposed as an alternative framework for specifying practically accessible assumptions beyond the MAR-MNAR dichotomy. However, there is currently no general algorithm for deciding how to handle the missing data given a spec

SUBMITTER: Moreno-Betancur M 

PROVIDER: S-EPMC6269242 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature