First Transcriptome Analysis of Iranian Scorpion, Mesobuthus Eupeus Venom Gland.

ABSTRACT: Scorpions are generally an important source of bioactive components, including toxins and other small peptides as attractive molecules for new drug development. Mesobuthus eupeus, from medically important and widely distributed Buthidae family, is the most abundant species in Iran. Researchers are interesting on the gland of this scorpion due to the complexity of its venom. Here, we have analyzed the transcriptome based on expressed sequence tag (EST) database from the venom tissue of Iranian M. eupeus by constructing a cDNA library and subsequent Sanger sequencing of obtained inserts. Sixty-three unique transcripts were identified, which were grouped in different categories, including Toxins (44 transcripts), Cell Proteins (9 transcripts), Antimicrobial Peptides (4 transcripts) and Unknow

SUBMITTER: Baradaran M 

PROVIDER: S-EPMC6269579 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature