Effect of an extruded animal protein-free diet on fecal microbiota of dogs with food-responsive enteropathy.

ABSTRACT:

Background

Dietary interventions are thought to modify gut microbial communities in healthy individuals. In dogs with chronic enteropathies, resolution of dysbiosis, along with remission of clinical signs, is expected with treatment.

Hypothesis/objective

To evaluate changes in the fecal microbiota in dogs with food-responsive chronic enteropathy (FRE) and in healthy control (HC) dogs before and after an elimination dietary trial with an animal protein-free diet (APFD).

Animals

Dogs with FRE (n = 10) and HC (n = 14).

Methods

Dogs were fed the APFD for 60 days. Fecal microbiota was analyzed by Illumina 16S rRNA sequencing and quantitative polymerase chain reaction (PCR).

Results

A significantly lower bacterial alpha-diversity was observed in dogs with FRE

SUBMITTER: Bresciani F 

PROVIDER: S-EPMC6271313 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature