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Two new lanostane triterpenoids from the branches and leaves of Polyalthia oblique.

ABSTRACT: Two new lanostane triterpenoids, 20-hydroxyeuphorbol-7-one (1) and 15α-hydroxyeuphorbol-7,11-dione (2), together with four known triterpenoids, euphorbol-7-one (3), friedelin (4), stigmast-4-ene-6α-ol-3-one (5), stigmasta-4-en-3,6-dione (6), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic analysis and comparisons with related known compounds. Antibacterial activities of two new compounds and four known compounds were tested.

SUBMITTER: Wang LK

PROVIDER: S-EPMC6271888 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature

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Two new lanostane triterpenoids from the branches and leaves of Polyalthia oblique.

Wang Liu-Kai LK Zheng Cai-Juan CJ Li Xiao-Bao XB Chen Guang-Ying GY Han Chang-Ri CR Chen Wen-Hao WH Song Xiao-Ping XP

Molecules (Basel, Switzerland) 20140606 6

Two new lanostane triterpenoids, 20-hydroxyeuphorbol-7-one (1) and 15α-hydroxyeuphorbol-7,11-dione (2), together with four known triterpenoids, euphorbol-7-one (3), friedelin (4), stigmast-4-ene-6α-ol-3-one (5), stigmasta-4-en-3,6-dione (6), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic analysis and comparisons with related known compounds. Antibacterial activities of two new ...[more]

PMID: 24914904

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