Polyphenolic Profile, Antioxidant and Anti-Inflammatory Activity of Eastern Teaberry (Gaultheria procumbens L.) Leaf Extracts.

ABSTRACT: Dry leaf extracts of eastern teaberry (Gaultheria procumbens L.) were evaluated as a source of bioactive phytocompounds through systematic activity testing and phytochemical profiling. The antioxidant efficiency was tested using five complementary in vitro models (DPPH; FRAP; linoleic acid (LA) peroxidation assay; O₂•- and H₂O₂ scavenging tests) in parallel with standard antioxidants. The 75% methanol extract and its diethyl ether, ethyl acetate (EAF), n-butanol and water fractions exhibited the dose-dependent responses in all assays, with the highest capacities found for EAF (DPPH EC₅₀ = 2.9 μg/mL; FRAP = 12.8 mmol Fe2+/g; IC₅₀ for LA-peroxidation = 123.9 μg/mL; O₂•- SC₅₀ = 3.9 μg/mL; H₂O₂ S

SUBMITTER: Michel P 

PROVIDER: S-EPMC6271927 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature