Synthesis of a Functionalized Benzofuran as a Synthon for Salvianolic Acid C Analogues as Potential LDL Antioxidants.

ABSTRACT: A palladium mediated synthesis of a common synthon for the syntheses of antioxidant analogues of naturally occurring salvianolic acids is presented. The synthetic route may be used to obtain analogues with a balanced lipophilicity/hydrophilicity which may result in potentially interesting LDL antioxidants for the prevention of cardiovascular diseases.

SUBMITTER: Lopez-Frias G 

PROVIDER: S-EPMC6272376 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature