Curcumin and Resveratrol in the Management of Cognitive Disorders: What is the Clinical Evidence?

ABSTRACT: A growing body of in vitro and in vivo evidences shows a possible role of polyphenols in counteracting neurodegeneration: curcumin and resveratrol are attractive substances in this regard. In fact, epidemiological studies highlight a neuroprotective effect of turmeric (rhizome of Curcuma longa L.), the main source of curcumin. Moreover, the consumption of red wine, the main source of resveratrol, has been related to a lower risk of developing dementia. In this review, we analyzed the published clinical trials investigating curcumin and resveratrol in the prevention or treatment of cognitive disorders. The ongoing studies were also described, in order to give an overview of the current search on this topic. The results of published trials (five for curcumin, six for resveratrol) are disappo

SUBMITTER: Mazzanti G 

PROVIDER: S-EPMC6273006 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature