Synthesis of Optically Active Poly(diphenylacetylene)s Using Polymer Reactions and an Evaluation of Their Chiral Recognition Abilities as Chiral Stationary Phases for HPLC.

ABSTRACT: A series of optically active poly(diphenylacetylene) derivatives bearing a chiral substituent (poly-2S) or chiral and achiral substituents (poly-(2S_x-co-3_1-x)) on all of their pendant phenyl rings were synthesized by the reaction of poly(bis(4-carboxyphenyl)acetylene) with (S)-1-phenylethylamine ((S)-2) or benzylamine (3) in the presence of a condensing reagent. Their chiroptical properties and chiral recognition abilities as chiral stationary phases (CSPs) for high-performance liquid chromatography (HPLC) were investigated. Poly-2S and poly-(2S_x-co-3_1-x) (0.06 < x < 0.71) formed a preferred-handed helical conformation with opposite hel

SUBMITTER: Maeda K 

PROVIDER: S-EPMC6273228 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature