Connectivity of the Human Number Form Area Reveals Development of a Cortical Network for Mathematics.

ABSTRACT: The adult brain contains cortical areas thought to be specialized for the analysis of numbers (the putative number form area, NFA) and letters (the visual word form area, VWFA). Although functional development of the VWFA has been investigated, it is largely unknown when and how the NFA becomes specialized and connected to the rest of the brain. One hypothesis is that NFA and VWFA derive their special functions through differential connectivity, but the development of this differential connectivity has not been shown. Here, we mapped the resting state connectivity of NFA and VWFA to the rest of the brain in a large sample (n = 437) of individuals (age 3.2-21 years). We show that within NFA-math network and within VWFA-reading network the strength of connectivity increases with age.

SUBMITTER: Nemmi F 

PROVIDER: S-EPMC6275176 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature