Dissecting the Genomic Architecture of Resistance to <i>Eimeria maxima</i> Parasitism in the Chicken.

ABSTRACT: Coccidiosis in poultry, caused by protozoan parasites of the genus Eimeria, is an intestinal disease with substantial economic impact. With the use of anticoccidial drugs under public and political pressure, and the comparatively higher cost of live-attenuated vaccines, an attractive complementary strategy for control is to breed chickens with increased resistance to Eimeria parasitism. Prior infection with Eimeria maxima leads to complete immunity against challenge with homologous strains, but only partial resistance to challenge with antigenically diverse heterologous strains. We investigate the genetic architecture of avian resistance to E. maxima primary infection and heterologous strain secondary challenge using White Leghorn populations of derived inbred l

SUBMITTER: Boulton K 

PROVIDER: S-EPMC6275401 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature