Electrical latency predicts the optimal left ventricular endocardial pacing site: results from a multicentre international registry.

ABSTRACT:

Aims

The optimal site for biventricular endocardial (BIVENDO) pacing remains undefined. Acute haemodynamic response (AHR) is reproducible marker of left ventricular (LV) contractility, best expressed as the change in the maximum rate of LV pressure (LV-dp/dtmax), from a baseline state. We examined the relationship between factors known to impact LV contractility, whilst delivering BIVENDO pacing at a variety of LV endocardial (LVENDO) locations.

Methods and results

We compiled a registry of acute LVENDO pacing studies from five international centres: Johns Hopkins-USA, Bordeaux-France, Eindhoven-The Netherlands, Oxford-United Kingdom, and Guys and St Thomas' NHS Foundation Trust, London-UK. In all, 104 patients incorporating 687 endocardial and 93 epicardial pacing locations

SUBMITTER: Sieniewicz BJ 

PROVIDER: S-EPMC6275469 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature