Cell size control driven by the circadian clock and environment in cyanobacteria.

ABSTRACT: How cells maintain their size has been extensively studied under constant conditions. In the wild, however, cells rarely experience constant environments. Here, we examine how the 24-h circadian clock and environmental cycles modulate cell size control and division timings in the cyanobacterium Synechococcus elongatus using single-cell time-lapse microscopy. Under constant light, wild-type cells follow an apparent sizer-like principle. Closer inspection reveals that the clock generates two subpopulations, with cells born in the subjective day following different division rules from cells born in subjective night. A stochastic model explains how this behavior emerges from the interaction of cell size control with the clock. We demonstrate that the clock continuously modulates the pro

SUBMITTER: Martins BMC 

PROVIDER: S-EPMC6275512 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature