Comparison of stereotactic body radiotherapy versus metastasectomy outcomes in patients with pulmonary metastases.

ABSTRACT:

Background

We compared the treatment outcomes of stereotactic body radiotherapy (SBRT) and metastasectomy in patients with pulmonary metastases.

Methods

Twenty-one patients received SBRT (total radiation doses 60 Gy in 3 fractions or 48 Gy in 4 fractions) and 30 underwent metastasectomy, most (93.3%) with wedge resection. The patients were followed for a median of 13.7 months. The tumor size in the SBRT group was larger than in the metastasectomy group (median 2.5 vs. 1.25 cm; P = 0.015). Patients with synchronous metastases were more likely to be treated with SBRT than with metastasectomy (P = 0.006).

Results

There was no significant difference in the local control rates of the treatment groups (P = 0.163). Progression-free survival (PFS) was longer in the metastasec

SUBMITTER: Lee YH 

PROVIDER: S-EPMC6275814 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature