Photodynamic therapy at ultra-low NIR laser power and X-Ray imaging using Cu₃BiS₃ nanocrystals.

ABSTRACT: Materials with efficient potential in imaging as well as therapy are gaining particular attention in current medical research. Photodynamic therapy (PDT) has been recently recognized as a promising treatment option for solid tumors. Still, most of the nanomaterial-based PDT modules either employ an additional photosensitizer or require high power laser sources. Also, they suffer from a lack of responsiveness in the near-infrared (NIR) region. Nanomaterials that could realize PDT independently (without any photosensitizer), at safe laser dose and in the deep tissue penetrative NIR region would definitely be better solid tumor treatment options. Methods: Herein, Cu- and Bi-based bimetal chalcogenide (Cu₃BiS₃), with absorption in the NIR region was developed. High

SUBMITTER: Veeranarayanan S 

PROVIDER: S-EPMC6276086 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature