Menstrual Dysfunction in Girls From the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study.

ABSTRACT:

Context

Little is known about reproductive function in girls with youth-onset type 2 diabetes.

Objectives

To characterize girls with irregular menses and effects of glycemic treatments on menses and sex steroids in the Treatment Options for Type 2 Diabetes in Youth (TODAY) study.

Design

Differences in demographic, metabolic, and hormonal characteristics between regular- vs irregular-menses groups were tested; treatment group (metformin with or without rosiglitazone, metformin plus lifestyle) effect on menses and sex steroids over time in the study was assessed. This is a secondary analysis of TODAY data.

Setting

Multicenter study in an academic setting.

Patients

TODAY girls not receiving hormonal contraception and those at least 1-year postmenarche were

SUBMITTER: Kelsey MM 

PROVIDER: S-EPMC6276678 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature