Midluteal Progesterone: A Marker of Treatment Outcomes in Couples With Unexplained Infertility.

ABSTRACT:

Context

Adequate luteal phase progesterone exposure is necessary to induce endometrial changes required for a successful pregnancy outcome. The relationship between low midluteal progesterone concentration and the outcome of live birth in ovarian stimulation with intrauterine insemination (OS-IUI) treatments is not defined.

Objective

To determine the level of midluteal progesterone portending a low chance of live birth after OS-IUI in couples with unexplained infertility.

Design and setting

Secondary analyses of data from a prospective, randomized, multicenter clinical trial that determined pregnancy outcomes following OS-IUI with clomiphene citrate, letrozole, or gonadotropins for couples with unexplained infertility.

Participants

Couples (n = 900) underwent 2

SUBMITTER: Hansen KR 

PROVIDER: S-EPMC6276712 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature