The correlation between AMH assays differs depending on actual AMH levels.

ABSTRACT:

Study question

What is the correlation of serum anti-Müllerian hormone (AMH) levels between two frequently used laboratory assays?

Summary answer

A considerable difference was found in serum AMH levels measured with the two different assays, particularly for low AMH values.

What is known already

AMH is regarded as being a robust, highly sensitive and specific biomarker for ovarian response and has become widely used as the basis for fertility treatment decisions. However, several available assays with different reference values, in addition to inter-laboratory variations and issues of sample stability, make interpretation of the AMH values and their clinical implications complicated.

Study design size duration

An observational study was performed including 269

SUBMITTER: Magnusson A 

PROVIDER: S-EPMC6277007 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature