Multimorbidity and co-morbidity in atrial fibrillation and effects on survival: findings from UK Biobank cohort.

ABSTRACT:

Aims

To examine the number and type of co-morbid long-term health conditions (LTCs) and their associations with all-cause mortality in an atrial fibrillation (AF) population.

Methods and results

Community cohort participants (UK Biobank n = 502 637) aged 37-73 years were recruited between 2006 and 2010. Self-reported LTCs (n = 42) identified in people with AF at baseline. All-cause mortality was available for a median follow-up of 7 years (interquartile range 76-93 months). Hazard ratios (HRs) examined associations between number and type of co-morbid LTC and all-cause mortality, adjusting for age, sex, socio-economic status, smoking, and anticoagulation status. Three thousand six hundred fifty-one participants (0.7% of the study population) reported AF; mean age was 61.9 ye

SUBMITTER: Jani BD 

PROVIDER: S-EPMC6277149 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature