Detecting cervical precancer and reaching underscreened women by using HPV testing on self samples: updated meta-analyses.

ABSTRACT:

Objective

To evaluate the diagnostic accuracy of high-risk human papillomavirus (hrHPV) assays on self samples and the efficacy of self sampling strategies to reach underscreened women.

Design

Updated meta-analysis.

Data sources

Medline (PubMed), Embase, and CENTRAL from 1 January 2013 to 15 April 2018 (accuracy review), and 1 January 2014 to 15 April 2018 (participation review).

Review methods

Accuracy review: hrHPV assay on a vaginal self sample and a clinician sample; and verification of the presence of cervical intraepithelial neoplasia grade 2 or worse (CIN2+) by colposcopy and biopsy in all enrolled women or in women with positive tests. Participation review: study population included women who were irregularly or never screened; women in the self samplin

SUBMITTER: Arbyn M 

PROVIDER: S-EPMC6278587 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature