Using competing risk and multistate model to estimate the impact of nosocomial infection on length of stay and mortality in burn patients in Southeast China.

ABSTRACT:

Objective

Due to the defects in skin barrier function and immune response, burn patients who survive the acute phase of a burn injury are at a high risk of nosocomial infection (NI). The aim of this study is to evaluate the impacts of NI on length of stay (LOS) and hospital mortality in burn patients using a multistate model.

Design and setting

A retrospective observational study was conducted in burn unit and intensive care unit in the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Participants

Data were obtained from 1143 records of patients admitted with burn between 1 January 2013 and 31 December 2016.

Methods

Risk factors for NIs were determined by binary logistic regression. The extended Cox model with time-varying covariates was

SUBMITTER: Guo HL 

PROVIDER: S-EPMC6278804 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature