Vitamin D and metabolic disturbances in polycystic ovary syndrome (PCOS): A cross-sectional study.

ABSTRACT:

Objective

To compare vitamin D status in women with PCOS versus fertile women and subsequently evaluate the association between vitamin D status and metabolic disturbances in PCOS women.

Methods

We conducted a cross-sectional comparison study of 639 women with PCOS and 449 fertile women. Serum 25-hydroxyvitamin D (25(OH)D) was stratified into a severe deficient (< 25 nmol/l), insufficient (25-50 nmol/l), moderate (50-75 nmol/l) and adequate (> 75 nmol/l) status. The main outcome measures were the difference in vitamin D status between PCOS and fertile women, and the association between serum 25(OH)D and metabolic disturbances in PCOS women only.

Results

Serum 25(OH)D was significantly lower in PCOS women compared to fertile controls (mean 25(OH)D of 49.0 nmol/l versus

SUBMITTER: Krul-Poel YHM 

PROVIDER: S-EPMC6279035 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature