Secular trends in semen parameters among men attending a fertility center between 2000 and 2017: Identifying potential predictors.

ABSTRACT:

Background

Multiple meta-analyses have shown sperm count declines in Western countries spanning eight decades. Secular trends in other parameters remain unclear, as are potential predictors of these trends.

Objective

To analyze secular trends in semen quality and to evaluate whether factors previously found to be related to semen quality were responsible for these patterns.

Methods

This is a prospective study including 936 men of couples seeking infertility treatment who provided 1618 semen samples at a single center (2000-2017). Self-reported demographic, nutritional and reproductive characteristics were collected using standardized questionnaires. Urinary concentrations of bisphenol A, parabens and phthalates were quantified by isotope-dilution tandem mass spectrome

SUBMITTER: Minguez-Alarcon L 

PROVIDER: S-EPMC6279498 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature