Dorsolateral and medial prefrontal cortex mediate the influence of incidental priming on economic decision making in obesity.

ABSTRACT: Obese individuals discount future rewards to a higher degree than lean individuals, which is generally considered disadvantageous. Moreover, their decisions are altered more easily by decision-irrelevant cues. Here, we investigated neural correlates of this phenomenon using functional MRI. We tested 30 lean and 26 obese human subjects on a primed delay discounting paradigm using gustatory and visual cues of positive, neutral and negative valence to bias their intertemporal preferences. We hypothesised that activation differences in reward-related and behavioural control areas, and changes in connectivity between these areas, would reflect the effect of these cues. Here, obese subjects were more susceptible to priming with negative gustatory cues towards delayed choices as opposed to lean s

SUBMITTER: Morys F 

PROVIDER: S-EPMC6279740 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature