The evolution of ependymin-related proteins.

ABSTRACT:

Background

Ependymins were originally defined as fish-specific secreted glycoproteins involved in central nervous system plasticity and memory formation. Subsequent research revealed that these proteins represent a fish-specific lineage of a larger ependymin-related protein family (EPDRs). EPDRs have now been identified in a number of bilaterian animals and have been implicated in diverse non-neural functions. The recent discoveries of putative EPDRs in unicellular holozoans and an expanded EPDR family with potential roles in conspecific communication in crown-of-thorns starfish suggest that the distribution and diversity of EPDRs is significantly broader than currently understood.

Results

We undertook a systematic survey to determine the distribution and evolution of EPDRs

SUBMITTER: McDougall C 

PROVIDER: S-EPMC6280359 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature