Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes.

ABSTRACT:

Background

Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage ≥3 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage ≥3 CKD in a large cohort of patients affected by T1DM.

Methods

A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretio

SUBMITTER: Mirijello A 

PROVIDER: S-EPMC6280443 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature