Influence of neutropenia on mortality of critically ill cancer patients: results of a meta-analysis on individual data.

ABSTRACT:

Background

The study objective was to assess the influence of neutropenia on outcome of critically ill cancer patients by meta-analysis of individual data. Secondary objectives were to assess the influence of neutropenia on outcome of critically ill patients in prespecified subgroups (according to underlying tumor, period of admission, need for mechanical ventilation and use of granulocyte colony stimulating factor (G-CSF)).

Methods

Data sources were PubMed and the Cochrane database. Study selection included articles focusing on critically ill cancer patients published in English and studies in humans from May 2005 to May 2015. For study selection, the study eligibility was assessed by two investigators. Individual data from selected studies were obtained from corresponding

SUBMITTER: Georges Q 

PROVIDER: S-EPMC6280476 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature