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Oncologic Procedures Amenable to Fluorescence-guided Surgery.


ABSTRACT:

Objective

Although fluorescence imaging is being applied to a wide range of cancers, it remains unclear which disease populations will benefit greatest. Therefore, we review the potential of this technology to improve outcomes in surgical oncology with attention to the various surgical procedures while exploring trial endpoints that may be optimal for each tumor type.

Background

For many tumors, primary treatment is surgical resection with negative margins, which corresponds to improved survival and a reduction in subsequent adjuvant therapies. Despite unfavorable effect on patient outcomes, margin positivity rate has not changed significantly over the years. Thus, patients often experience high rates of re-excision, radical resections, and overtreatment. However, fluorescen

SUBMITTER: Tipirneni KE 

PROVIDER: S-EPMC6280663 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature