Dual-time-point FDG PET/CT imaging in prosthetic heart valve endocarditis.

ABSTRACT:

Purpose

FDG PET/CT has been of increasing interest in the diagnostic workup of prosthetic heart valve endocarditis (PVE). Some reports advocate later imaging time points to improve the diagnostic accuracy for PVE. In this study, we compared standard and late FDG PET/CT images in patients with a clinical suspicion of PVE.

Materials and methods

Fourteen scans in 13 patients referred for FDG PET/CT for suspicion of PVE performed at standard (60 min post injection) and late (150 min post injection) time points were scored based on visual interpretation and semi-quantitatively with SUVmax and target-to-background ratio (TBR, defined as [SUVmax valve/SUVmean blood pool]). Final diagnosis was based on surgical findings in all cases of infection (n = 6) and unremarkable follow-up in

SUBMITTER: Scholtens AM 

PROVIDER: S-EPMC6280957 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature