Four 1-aryl-1H-pyrazole-3,4-di-carboxyl-ate derivatives: synthesis, mol-ecular conformation and hydrogen bonding.

ABSTRACT: Four 1-aryl-1H-pyrazole-3,4-di-carboxyl-ate derivatives, one acid, two esters and a dicarbohydrazide have been synthesized starting from 3-aryl sydnones, and structurally characterized. There is an intra-molecular O-H⋯O hydrogen bond in 1-phenyl-1H-pyrazole-3,4-di-carb-oxy-lic acid, C₁₁H₈N₂O₄, (I), and the mol-ecules are linked into a three-dimensional framework structure by a combination of O-H⋯O, O-H⋯N, C-H⋯O and C-H⋯π(arene) hydrogen bonds. In each of the two esters dimethyl 1-phenyl-1H-pyrazole-3,4-di-carboxyl-ate, C₁₃H₁₂N₂O₄, (II), and dimethyl 1-(4-methyl-phen-yl)-1H-pyrazole-3,4-di-carboxyl-ate, C₁₄H₁₄N₂O₄, (III), C-H⋯O hydro

SUBMITTER: Asma 

PROVIDER: S-EPMC6281123 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature