Boolean Calcium Signalling Model Predicts Calcium Role in Acceleration and Stability of Abscisic Acid-Mediated Stomatal Closure.

ABSTRACT: Inconsistent hypotheses have proposed Ca²⁺ as either being essential or irrelevant and redundant in ABA induced stomatal closure. This study integrates all available information from literature to define ABA signalling pathway and presents it in a systems view for clearer understanding of the role of Ca²⁺ in stomatal closure. Importantly, it incorporates into an Asynchronous Boolean model time delays sourced from an extensive literature search. The model predicted the timing of ABA events and mutant behaviour close to biology. It revealed biologically reported timing for Ca²⁺ activation and Ca²⁺ dynamics consistent with biology. It also predicts that Ca²⁺ elevation is not essential in stomatal closure but it can accelerate closure, con

SUBMITTER: Waidyarathne P 

PROVIDER: S-EPMC6281740 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature