High risk of peri-implant disease in periodontal Ehlers-Danlos Syndrome. A case series.

ABSTRACT:

Objectives

Periodontal Ehlers-Danlos syndrome (pEDS) has recently been delineated as a molecularly defined cause of early severe periodontitis. Here we report that implant treatment failed in three affected individuals from one family.

Materials and methods

Longitudinal data before and after implant treatment were examined for three individuals with genetically confirmed pEDS in the course of a large-scale pedigree analysis.

Results

Most detailed information was available for individual 1 in whom first periodontal bone loss was diagnosed at age 16 years. Rapid progression resulted in multiple tooth extractions at age 23 years and interforaminal placement of four implants. After primary implant success, peri-implant bone loss accompanied by highly inflamed tissues and

SUBMITTER: Rinner A 

PROVIDER: S-EPMC6282529 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature