Separating fetal and maternal placenta circulations using multiparametric MRI.

ABSTRACT:

Purpose

The placenta is a vital organ for the exchange of oxygen, nutrients, and waste products between fetus and mother. The placenta may suffer from several pathologies, which affect this fetal-maternal exchange, thus the flow properties of the placenta are of interest in determining the course of pregnancy. In this work, we propose a new multiparametric model for placental tissue signal in MRI.

Methods

We describe a method that separates fetal and maternal flow characteristics of the placenta using a 3-compartment model comprising fast and slowly circulating fluid pools, and a tissue pool is fitted to overlapping multiecho T2 relaxometry and diffusion MRI with low b-values. We implemented the combined model and acquisition on a standard 1.5 Tesla clinical system with acqu

SUBMITTER: Melbourne A 

PROVIDER: S-EPMC6282748 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature